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Cecilia Ana Suárez

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Dra. Cecilia Ana Suárez

csuarez@dc.uba.ar

  

 


Biological Sciences, PhD

 

Adjunct Researcher CONICET

Research area: Mathematical-numerical modelling of tumor growth and its treatment by electric fields

 

Scientific background:

 

2014-2015: Adjunct Researcher CONICET

Mathematical modeling of tumor growth and treatment

Laboratorio de Sistemas Complejos, Departamento de Computación

Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires

2007-2013: Assistant Researcher CONICET

Mathematical modeling of electrochemical treatment of tumors

Laboratorio de Sistemas Complejos, Departamento de Computación

Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires

Director: Guillermo Marshall

2006-2007: Postdoctoral fellowship ANPCyT

Electrochemical treatment of tumors

Laboratorio de Sistemas Complejos, Departamento de Computación

Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires

Director: Guillermo Marshall

2005-2006: Postdoctoral fellowship ANPCyT

Stem cell transplant in Parkinson disease

Instituto de Investigaciones Bioquímicas Fundación Leloir

Director: Fernando Pitossi

2004-2005: Ramón Carrillo -  Arturo Oñativia fellowship for young researchers

Ministerio de Salud de la Nación

Instituto de Biologia y Medicina Experimental

Director: Damasia Becu-Villalobos

2000-2004: Doctoral fellowship CONICET

Hormonal regulation of pituitary tumors

Instituto de Biologia y Medicina Experimental

Director: Damasia Becu-Villalobos

 

Full Papers:

 

 GAL3ST2 from mammary gland epithelial cells affects differentiation of 3T3-L1 preadipocytes; Guerra Liliana, Suarez Cecilia, Soto Daniela, Schiappacasse Agustina, Sapochnik Daiana, Sacca Paula, Piwien-Pilipuk Graciela, Peral Belen, Calvo Juan Carlos; Clinical & Translational Oncology 17(7): 511-520, 2015

 The role of additional pulses in electropermeabilization protocols; Suarez Cecilia, Soba Alejandro, Maglietti Felipe, Olaiz Nahuel, Marshall Guillermo; Plos One 9(12): e113413, 2014

 Tissue damage modeling in gene electrotransfer: the role of pH; Olaiz Nahuel, Signori Emanuella, Maglietti Felipe, Soba Alejandro, Suárez Cecilia, Turjanski Pablo, Michinski Sebastián, Marshall Guillermo; Bioelectrochemistry 100: 105-111, 2014

 The role of pH fronts in tissue electroporation based treatments; Maglietti F, Michinski S, Olaiz N, Castro M, Suárez C, Marshall G; PlosOne 8(11): e80167, 2013

  Mathematical modeling of human glioma growth based on brain topological structures: study of two clinical cases; Suárez Cecilia, Maglietti Felipe, Colonna Mario, Breitburd Karina, Marshall Guillermo; PlosOne 7(6): e39616, 2012

 The role of pH fronts in reversible electroporation; Turjanski Pablo, Olaiz Nahuel, Maglietti Felipe, Michinski Sebastián, Suárez Cecilia, Molina Fernando, Marshall Guillermo; Plos One 6(4): e17303, 2011

 Electrochemical treatment of tumors using a one-probe two-electrode device; Olaiz Nahuel, Maglietti Felipe, Suárez Cecilia, Molina Fernando, Miklavcic Damijan, Mir Lluis, Marshall Guillermo; Electrochimica Acta 55 (20): 6010-6014, 2010

 When the optimal is not the best: parameter estimation in complex biological models; Fernández-Slezak Diego, Suárez Cecilia, Cecchi Guillermo, Marshall Guillermo, Stolovitzky Gustavo; Plos One 5 (10): e13283, 2010

 Tracking protein electrodenaturation fronts in the electrochemical treatment of tumors; Olaiz Nahuel, Suárez Cecilia, Risk Marcelo, Molina Fernando, Marshall Guillermo; Electrochemistry Communications 12 (1): 94–97, 2010

pH front tracking in the electrochemical treatment (EChT) of tumors: experiments and simulations; Turjanski Pablo, Olaiz Nahuel, Abou-Adal Pablo, Suárez Cecilia, Risk Marcelo, Marshall Guillermo; Electrochimica Acta 54 (26): 6199-6206, 2009

 1on transport in tumors under electrochemical treatment: in vivo, in vitro and in silico modeling; Colombo Lucas, González Graciela, Marshall Guillermo, Molina Fernando, Soba Alejandro, Suárez Cecilia, Turjanski Pablo; Bioelectrochemistry 71 (2): 223-232, 2007

 Dehydroepiandrosterone modulates GHRH, somatostatin and angiotensin II action at the pituitary level; Suárez Cecilia, Vela Jorge, García-Tornadú Isabel, Becú-Villalobos Damasia; Journal of Endocrinology 185 (1): 165-172, 2005

 Upregulation of angiotensin II type 2 receptor expression in estrogen induced pituitary hyperplasia; Suárez Cecilia, Díaz-Torga Graciela, González-Iglesias Arturo, Cristina Carolina, Becú-Villalobos Damasia; American Journal of Physiology (Endocrinology and Metabolism) 286 (5): E786-794, 2004.

 Angiotensin II phosphorylation of extracellular signal regulated kinases in rat anterior pituitary cells; Suárez Cecilia, Díaz-Torga Graciela, González-Iglesias Arturo, Vela Jorge, Mladovan Alejandro, Baldi Alberto, Becú-Villalobos Damasia; American Journal of Physiology (Endocrinology and Metabolism) 285 (3): E645-653, 2003.

 Dehydroepiandrosterone treatment attenuates estrogen induced pituitary hyperplasia; Suárez Cecilia, García-Tornadú Isabel, Khalil Wahid, Becú-Villalobos Damasia; Journal of Endocrinology 174 (3): 447-454, 2002

 Angiotensin and calcium signaling in the pituitary and hypothalamus; Suárez Cecilia, García-Tornadú Isabel, Cristina Carolina, Vela Jorge, González-Iglesias Arturo, Libertun Carlos, Díaz-Torga Graciela; Becú-Villalobos Damasia; Cellular and Molecular Neurobiology  22 (3): 315-333, 2002.

 Desensitization of angiotensin II: effect on [Ca2++]i, inositol triphosphate and prolactin in pituitary cells; González-Iglesias Arturo, Suárez Cecilia, Feierstein Claudia, Díaz-Torga Graciela, Becú-Villalobos Damasia; American Journal of Physiology (Endocrinology and Metabolism) 280 (3): E462-E470, 2001

 

Short papers, oral presentations and posters since 2010:


 Mathematical modeling in tumor biology; Dissertation in the context of the "Interphase Seminaries: between mathematics, informatics and natural sciences" at the Calculus Institute, FCEyN, UBA, April 2015

 In silico generation of tumor invasion patterns; E Lujan, A Soba, N Visacovsky, L Guerra, G Marshall, C Suárez; Poster presented at the VI Argentinian Conference on Bioinformatics and Computational Biology, Bahia Blanca, October 2015; and at the Latin American Conference on Mathematical Modeling of Biological Systems, Buenos Aires, December 2015

 Effects of pulse addition in electropermeabilization: Theoretical insights on the electric conductivity; C Suárez, A Soba, F Maglietti, N Olaiz, G Marshall; short paper presented at the 1st World Congress on Electroporation and Pulsed Electric Fields in Biology, Medicine and Food & Environmental Technologies; Portoroz, Slovenia, September 2015. Published in IFMBE Proceedings 53: 215-218, 2015

 GET protocols: Hyaluronidase is an effective adjuvant in the permeabilization of muscle fibers; N Olaiz, E Signori, L Guerra, F Maglietti, C Suárez, M Villaverde, L Colombo, S Michinski, G Marshall; Poster presented at the 1st World Congress on Electroporation and Pulsed Electric Fields in Biology, Medicine and Food & Environmental Technologies; Portoroz, Slovenia, September 2015.

 The role of pH gradients in tissue electroporation-based treatments; F Maglietti, S Michinski, N Olaiz, M Castro, C Suárez, G Marshall, Poster presented at the Annual Meeting of Bioelectromagnetics Society (BioEM 2015), California, EEUU, June 2015

 Modelado numérico de la invasión de tumores de estadio avascular; C Suárez, A Schiappacasse, L Guerra, A Soba, G Marshall; Poster presented at the 6ta. Escuela Argentina de Matemática y Biología (BIOMAT), Córdoba, Agosto 2014; and at the International Workshop of the Raices Program "Mathematics as a tool to understand biology, biology as a source of mathematic problems", Buenos Aires, April 2015

 The role of pH fronts in vaccination protocols based on electroporation; G Marshall, N Olaiz, E Signori, F Maglietti, A Soba, C Suárez, P Turjanski, S Michinski; Poster presented at the 14th International Conference on Progress In Vaccination against Cancer PIVAC -14, Roma, Italia, Septiembre 2014

 Tissue damage in vaccination protocols based on electroporation: pH fronts and tissue natural buffering; M Marino, N Olaiz, E Signori, F Maglietti, C Suárez, L Colombo, P Turjanski, S Michinski, E Luján, G Marshall; Poster presented at the 14th International Conference on Progress in Vaccination against Cancer PIVAC-14 Roma, Italia, Septiembre 2014

 Patrón de invasión de esferoides multicelulares de la línea LM3 inmersos en matriz tridimensional de colágeno I; A Schiappacasse, L Guerra, JC Calvo, G Marshall, C Suárez; Poster presented at the LVIII Reunión Científica Anual de la Soc. Arg. de Investigación Clínica (SAIC), Mar del Plata, Bs. As, 2013; Published in Medicina 73 Supl III: 140, abstract 172, 2013

 EGT protocols: the role of electroporation based techniques, hyaluronidase and pH effects in the permeabilization of tissue fibers; N Olaiz, E Signori, F Maglietti, A Soba, L Guerra, C Suárez, L Colombo, P Turjanski, S Michinski, G Marshall; Poster presented at the COST Symposium on Electroporation and Biomedical Applications and MC Meeting; Bochum, Alemania, 2013

 Modelado numérico de la evolución del glioma y su tratamiento por electroquimioterapia (ECT); C Suárez, A Soba, F Maglietti, G Marshall; Poster presented at the 5ta. Escuela Arg. de Matemática y Biología (BIOMAT), La Falda, Córdoba, 2012

 Posible participación de la galactosa 3-O-sulfotransferasa-2 en procesos relacionados con la diferenciación de adipocitos; A Schiappacasse, B Peral, C Suárez, G Marshall, JC Calvo, L Guerra; Poster presented at the LVII Reunión Anual de la Soc. Arg. de Investigación Clínica (SAIC), Mar del Plata, Bs. As, 2012; Published in Medicina 72 supl II: 89, abstract 127, 2012

 Aproximación numérica a la electroporación reversible e irreversible combinada; E Mocskos, N Olaiz, F Maglietti, S Michinski, M Castro, C Suárez, F Molina, G Marshall; Abstract presented at the X Congreso Argentino de Mecánica Computacional (MECOM), Salta, 2012

 pH changes induced by EGT and ECT pulse delivery in tissues; F Maglietti, S Michinski, N Olaiz, M Castro, C Suárez, G Marshall; Poster presented at the Gordon Research Conference in Bioelectrochemistry, Barga, Italy, 2012

 Modelado matemático-numérico del desarrollo del glioma en humanos; Oral presentation at the 2do. Congreso Arg. de Bioinformática y Biología Computacional, Córdoba, 2011

 Efectos del campo eléctrico alterno sobre la migración celular y la cicatrización tisular; N Olaiz, L Colombo, L Guerra, JC Calvo, G Marshall, C Suárez; Poster presented at the XXVII Jornadas Multidisciplinarias de Oncología del Instituto Angel H. Roffo, Bs. As, 2011

 Electrochemical treatment of tumors: tracking study of electrodenaturation fronts propagating from a one-probe two-electrode device (OPTED); Olaiz N, Maglietti F, Suárez C, Molina F, Marshall G; Poster presented at the Annual Meeting of the International Society of Electrochemistry, Niza, Italy, 2010

 The role of pH fronts in electrotherapy and electrochemotherapy; Maglietti F, Turjanski P, Olaiz N, Michinski S, Suárez C, Molina F, Marshall G; Abstract presented at the Workshop on Electric Field Effects in Tumors: Biophysical Foundations and Clinical Experiences de la 32nd Annual International Conference of the IEEE Engineering in Medicine and Biology Society; Universidad de Buenos Aires, 2010

 Ion transport studies in the electrochemical treatment of tumors: experiments and simulations; Maglietti F, Turjanski P, Olaiz N, Michinski S, Suárez C, Molina F, Marshall G; Poster presented at the Gordon Research Conference in Bioelectrochemistry “The complex membrane in the electric field”, University of New England, Maine, United States, 2010

 Terapias alternativas contra el cáncer basadas en la aplicación de campos eléctricos; Marshall G, Suárez C; Research note published in Revista Ciencia Hoy 20: 42-49, February-March 2010

 

Human research formation:

 

Director of a CONICET doctoral fellowship, Maximiliano Geier, in course.

Director of an INC fellowship, Nicolás Visacovsky, in course.

Director of a CIN fellowship 2012 and 2013, Agustina Schiappacasse.

Member of the Doctoral Commission at the Engineering Faculty, Buenos Aires University, for the doctoral program monitoring of Sergio Liberczuk, in course.

Codirector of the Doctoral Thesis “Electroquimioterapia aplicada a tumores”, Nahuel Olaiz, School of Medicine, University of Buenos Aires, defended in March 2011

 

University lectures:


2014-2015: Introduction to Comsol Modeling, Complex Systems in Paralele Machines course, Computational Sciences career, Buenos Aires University.
2008-2013: Introduction to the Mathematical Modeling in Tumor Biology,
Complex Systems in Paralele Machines course, Computational Sciences career, Buenos Aires University.
2001-2003: Introduction to Neurosteroids, Clinic Biochemistry career, School of Pharmacy and Biochemistry, Buenos Aires University.

Participation in scientific activities:


Member of the Editorial Board of the Universal Journal of Applied Sciences (http://www.hrpub.org/journals/jour_info.php?id=29)

Member of the Directive Commission of the Argentine Cell Bank Association (ABAC) (http://www.abac.org.ar)